Fusidic acid(Fusidate or SQ-16603 and Fusidine)

Fusidic acid(Fusidate or SQ-16603 and Fusidine) Price And Quantity
- 1200 USD ($)/Kilograms
- 20 Ton
- 300.00 - 2800.00 USD ($)/Kilograms
Fusidic acid(Fusidate or SQ-16603 and Fusidine) Trade Information
- Shanghai China
- Telegraphic Transfer (T/T)
- 600 Ton Per Month
- 3 Days
- Within a certain price range free samples are available
- 1kg/bottle
- North America South America Western Europe Eastern Europe Middle East Africa Central America Asia Australia
- All India
- COA
Product Description
Product name:Fusidic acid(Fusidate;SQ-16603;Fusidine)
CAS:6990-06-3
MF:C31H48O6
MW:516.72
Description: Fusidic acid forms a stable complex with an elongation factor (EF-G) involved in translocation and with guanosine triphosphate (GTP), which provides energy for the translocation process. One round of translocation occurs, with hydrolysis of GTP, but the fusidic acid EF-GGDP complex cannot dissociate from the ribosome, thereby blocking further chain elongation and leaving peptidyl-tRNA in the P site.
Although protein synthesis in Gram-negative bacilli and, indeed, mammalian cells is susceptible to fusidic acid, the antibiotic penetrates poorly into these cells and the spectrum of action is virtually restricted to Gram-positive bacteria, notably staphylococci.
Fusidic acid is a bacteriostatic antibiotic. Fusidic Acid suppresses nitric oxide lysis of pancreatic islet cells. Inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA.